EDAPT Introduction to Pharmacology Practice Test

The metabolism of a drug through the cytochrome P450 system is indeed significantly influenced by an individual's genetics. The cytochrome P450 enzymes are a family of enzymes involved in the metabolism of many medications. Variations in genes that code for these enzymes can lead to differences in how individuals metabolize drugs, affecting drug efficacy and the risk of adverse effects.

For instance, some individuals may be classified as "poor metabolizers," meaning they metabolize certain drugs more slowly due to genetic variations. As a result, these individuals might experience increased drug levels in their system, leading to enhanced effects or toxicity. Conversely, "ultra-rapid metabolizers" may process drugs too quickly, resulting in subtherapeutic effects. Understanding a patient's genetic makeup can help healthcare providers tailor drug choices and dosages to improve therapeutic outcomes and minimize risks.

Other options presented, such as the physical appearance of the drug, the brand name, and the price, are not influenced by genetics. The physical appearance is determined by the manufacturer’s formulation and does not vary from person to person. The brand name is a marketing decision and does not reflect the pharmacological action of the drug or individual differences in metabolism. Similarly, drug pricing is a factor influenced by market conditions,