What is the correct duration for the insulin type Glargine?

Insulin Glargine is a long-acting insulin that is designed to provide a steady release of insulin over an extended period, typically lasting up to 24 hours. This makes it effective for maintaining basal insulin levels throughout the day and night, which is particularly beneficial for individuals with diabetes who need to manage their blood glucose levels continuously.

Glargine's pharmacokinetic profile includes a gradual onset and a plateau of activity, distinguishing it from intermediate-acting insulins that may cause peaks in insulin levels. The 24-hour duration is critical in achieving stable glucose control with minimal risk of hypoglycemia due to its peakless delivery.

Other insulin types have different durations. For example, rapid-acting insulins last a few hours, while intermediate-acting insulins like NPH typically last about 10 to 16 hours. By understanding the pharmacodynamics of insulin Glargine, it becomes clear why its duration is appropriately classified as around 24 hours.